I'm also on Win 10 pro,
I downloaded the recent beta of FL Studio just a week ago,
Reaper is 5.5,
Soundbridge is a free, open source DAW.
I remember that at one time Maik said something about external dependencies (some Microsoft dlls, probably Visual Studio), and that they have to be bundled with each plugin, because they are needed to run it. I don't have those externals and since I also don't play recent games on my PC, I don't have them installed from that side either. If the issues disappear with those externals, it would be great. So, please ask which ones are needed and bundle an installer for them with your plugin. I will happily try again then!
Those externals would also explain why you don't have any issues (you needed them already for Flowstone), and why not everyone has issues (some people will have them installed already for other apps (probably games) that also required them.